When mad AIOLOS drags IKAROS down: A novel pathogenic mechanism

Primary immunodeficiencies, such as severe combined immunodeficiency disease (SCID), occur when the immune system does not work properly, leading to increased susceptibility to various infections, autoimmunity, and cancers. Most of these are inherited and have an underlying genetic causes. A team at TMDU has identified a novel disorder resulting from a mutation in a protein… Read More »

Harvard Chan School professor discusses Delta variant

The Delta variant of the coronavirus has been spreading rapidly throughout the U.S. and worldwide. William Hanage, associate professor of epidemiology and a faculty member of the Center for Communicable Disease Dynamics at Harvard T.H. Chan School of Public Health, discusses the threat. Chan School: You were recently quoted on PRI’s The World as saying, “The… Read More »

Human cells harness power of detergents to wipe out bacteria

Cells, like many of us, fend off germs with cleaning products. Researchers have discovered that a molecule made throughout much of the body wipes out invading bacteria like a detergent attacking an oily stain. This killer cleaner, a protein known as APOL3, thwarts infections by dissolving bacterial membranes, Howard Hughes Medical Institute Investigator John MacMicking… Read More »